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Tuscany · Viator
Three real bookings in three places — the Uffizi in Florence, a Siena and Pisa countryside day, and Chianti tastings. They do not all leave from Pisa. You book Viator; we earn a commission at no extra cost to you.
Arrival night · Trip.com
Land at PSA, sleep in Pisa with somewhere to leave the car, then drive Tuscany in the morning. Searched on Trip.com.
Pisa Airport (PSA) car hire for Tuscany · Collecting at the airport? Compare Pisa Airport cars on DiscoverCars →
Find your Italy adventure by what you want to see.

Best time: April – June and September – October

Best time: Year-round; early or late slots are coolest

Best time: Year-round; early morning is far quieter

Best time: Spring and autumn; high water possible in winter

Best time: April – June and September – October

Best time: May – October

Best time: Spring and autumn; little shade in summer
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PSA first for Tuscany — Chianti, Siena, the Val d’Orcia. Rome, Milan and Florence stay on the compare page. Free cancellation on most bookings.
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Staying over
Parking-friendly first night after PSA — sleep in Pisa, leave the car, then drive Tuscany in the morning. Searched on Trip.com.
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Getting there
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Italy’s money path on this site is Pisa into Tuscany — collect at PSA, then the Uffizi in Florence, a Siena and Pisa countryside day, and Chianti tastings. Rome and Florence stay walkable city breaks; hire the car when you leave town. Whether you have a long weekend or a fortnight, there’s an experience worth booking.
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Everything you need to know before you book.
Florence and Rome centres are walking, metro and timed tickets. A hire car there is a ZTL and a parking bill, not a shortcut. The train covers the Pisa–Florence–Rome spine. Hill towns off that line — Chianti, San Gimignano, the Val d’Orcia — are where a car wins. If the itinerary leaves the rail spine, compare Pisa Airport (PSA) pickup. Pisa Airport car hire for Tuscany →
A full driving licence in the lead driver’s name, a passport or ID, and the card the booking names for the deposit hold. Compare Pisa Airport (PSA) first — the offer lists any International Driving Permit rule and the minimum age. We are not the rental company. Compare Pisa Airport cars →
The supplier places a hold on a credit card in the lead driver’s name. The amount depends on the car and the excess, so read the hold on the Pisa Airport (PSA) offer rather than a fixed figure. Photograph the car before you leave the lot. Compare Pisa Airport cars →
Yes. Both use timed entry and both routinely sell out in season, and the Vatican Museums queue without a booking is one of the longest in Europe. A guided tour with skip-the-line entry is the usual way visitors handle both.
It can be done, but it’s a very long day — most of it spent travelling. Naples, Sorrento or the coast itself make far better bases. From Rome, Pompeii is the more realistic single-day version of that trip.
A full day covers the Duomo, the Uffizi and the centre on foot if you’ve pre-booked the museums. Two days lets you add the Accademia and a half-day into the Tuscan hills or Chianti without rushing.
Your booking is held by the tour operator who runs the tour — you book and pay them directly through us — so cancellations and changes go through them, under the cancellation terms you agree to at checkout. Many operators offer free cancellation up to 24 hours before departure, but it varies by tour, so check the terms before you book.
Rome, Florence and Venice run close to capacity from spring through October, and timed-entry sights go first. Book as early as your dates are confirmed to secure your preferred departure.